A patient with worsening angina despite nitroglycerin should be referred to what?

When a patient is experiencing worsening angina that does not respond to nitroglycerin, it can indicate a more serious underlying issue, such as unstable angina or impending myocardial infarction. In such cases, immediate medical evaluation is essential. Referring the patient to the nearest emergency department ensures that they receive urgent care to assess their condition, provide necessary interventions, and monitor for any complications.

The other options may be considered in different contexts for managing chronic angina, but in the face of worsening symptoms unresponsive to treatment, the priority is to ensure the patient is evaluated by a healthcare professional equipped to handle potential acute coronary syndrome. This proactive approach is critical to prevent more severe consequences and ensures appropriate management is initiated swiftly.