Clindamycin use is notably associated with which gastrointestinal issue?

Clindamycin is an antibiotic commonly used to treat certain types of bacterial infections. One of the significant gastrointestinal side effects associated with clindamycin usage is diarrhea. This is particularly important because clindamycin can disrupt the normal gut flora, leading to an overgrowth of organisms like Clostridium difficile, which may result in antibiotic-associated diarrhea or, in severe cases, pseudomembranous colitis.

It's crucial for healthcare providers and patients to be aware of this potential side effect when initiating treatment with clindamycin. Monitoring for changes in bowel habits and advising on the signs of more severe gastrointestinal complications can be critical to patient safety and management.