For a 76-year-old man with hypertension and angina, which medication is most appropriate?

In the context of treating a 76-year-old man with both hypertension and angina, the selection of amlodipine is particularly appropriate due to its dual efficacy. Amlodipine is a calcium channel blocker that effectively lowers blood pressure and has proven benefits in angina management by reducing myocardial oxygen demand. It works by causing vasodilation of peripheral blood vessels and improving blood flow to the heart.

Older patients can often have a complex interplay of cardiovascular conditions, and amlodipine has a favorable side effect profile, particularly because it does not typically cause significant bradycardia or heart block, which can be concerns with some other medications used for these conditions. Its once-daily dosing can also improve adherence in elderly patients, who may struggle with complex medication regimens.

In comparison, while verapamil is also a calcium channel blocker and would aid in controlling both hypertension and angina, it can cause bradycardia and may not be as well tolerated in older patients, particularly those with conduction issues.

Ranolazine is primarily used for chronic angina but does not have significant effects on blood pressure, making it less suitable in a hypertensive patient. Metoprolol, a beta-blocker, is effective for angina