In a case of suspected cocaine overdose, what symptom is most likely to be present?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

In cases of suspected cocaine overdose, hypertension is the symptom that is most commonly associated with this drug's effects. Cocaine is a powerful stimulant that increases levels of norepinephrine in the body, leading to vasoconstriction and increased heart rate, both of which contribute to elevated blood pressure.

Stimulant effects of cocaine can cause a range of cardiovascular issues, including tachycardia and hypertension, which can be severe and potentially life-threatening. This is due to cocaine's action as a sympathomimetic agent that activates the sympathetic nervous system, resulting in increased vascular tone and heart contractility.

The other symptoms mentioned, such as bronchoconstriction, bradycardia, and miosis, are typically not associated with cocaine overdose. Instead, they may be seen in exposure or overdose situations involving other substances, such as opioids or certain types of inhalants, which produce different physiological effects. Thus, hypertension stands out as the most indicative symptom in cocaine overdose scenarios.

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