What is a potential effect of blocking sympathetic ganglia?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

Blocking sympathetic ganglia has a significant impact on the autonomic nervous system, particularly on the sympathetic branch, which is responsible for the "fight or flight" response. When sympathetic ganglia are blocked, the usual neurotransmitters that promote vasoconstriction and increase heart rate are inhibited.

This results in a decrease in the overall sympathetic tone in the body. Specifically, blood vessel dilation occurs due to the absence of sympathetic stimulation, leading to a reduction in peripheral vascular resistance. Consequently, this reduction in resistance lowers blood pressure. Additionally, without the sympathetic drive, the heart rate can also decrease; however, the most prominent and immediate effect associated with blocking sympathetic ganglia is the reduction in blood pressure.

This pharmacological principle is often exploited in medical situations where high blood pressure is a concern, and such medications can be integral to managing hypertensive crises or in the treatment of certain cardiovascular conditions. Thus, recognizing that blocking sympathetic ganglia primarily leads to a decrease in blood pressure is essential in understanding its physiological implications.

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