What is the main action of atropine?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

Atropine primarily acts as a cholinergic antagonist, which means it blocks the action of acetylcholine at muscarinic receptors in the parasympathetic nervous system. This inhibition leads to various physiological effects, such as increased heart rate, dilation of pupils (mydriasis), reduced secretions, and a reduction in gastrointestinal motility.

By antagonizing muscarinic receptors, atropine counteracts the effects of the parasympathetic nervous system, which is responsible for slowing the heart rate and promoting digestion, among other functions. This mechanism of action makes atropine useful in treating bradycardia (slow heart rate) and as an antidote for organophosphate poisoning, where excessive acetylcholine is present.

The other answer choices do not align with atropine's pharmacological properties. It is not a cholinergic agonist, which would stimulate acetylcholine receptors. Similarly, it does not act as an adrenergic agonist or antagonist, as those classifications pertain to the sympathetic nervous system and involve interactions with adrenergic receptors related to catecholamines like epinephrine and norepinephrine. Thus, atropine's specific role as a cholinergic antagonist underscores its therapeutic applications and relevance in

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