What is the main purpose of using somatostatin analogs in clinical practice?

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Somatostatin analogs primarily serve to decrease growth hormone secretion. These synthetic peptides mimic the action of somatostatin, a naturally occurring hormone that inhibits the release of various other hormones, including growth hormone from the pituitary gland. In conditions where there is excess growth hormone, such as acromegaly or certain types of tumors, somatostatin analogs can effectively reduce hormone levels, helping to alleviate symptoms and complications associated with these conditions.

Their role in decreasing growth hormone secretion is critical in managing disorders related to hypersecretion. By binding to somatostatin receptors on pituitary cells, these analogs suppress the pulsatile release of growth hormone, leading to improved clinical outcomes for patients affected by excessive hormone levels.

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