What is the preferred treatment method for ADHD that avoids multiple doses throughout the day?

The preferred treatment method for ADHD that avoids multiple doses throughout the day is the transdermal delivery system of methylphenidate. This formulation provides a continuous release of the medication throughout the day, allowing for steady plasma levels and symptom control without the need for several doses. Patients benefit from the convenience of applying a patch once daily, which enhances adherence to the treatment regimen.

In contrast, immediate-release formulations like mixed amphetamine salts and methylphenidate in pill form require multiple doses during the day to maintain effective symptom management, which can be challenging for some patients. The nicotine option does not pertain to the treatment of ADHD and is unrelated to its management. Thus, the transdermal delivery system of methylphenidate stands out as the best option that minimizes dosing frequency and improves patient compliance.