What is the primary advantage of urinary alkalinization in treating salicylate toxicity?

The primary advantage of urinary alkalinization in treating salicylate toxicity is that it promotes renal clearance of the drug. Salicylates, such as aspirin, are weak acids, and their solubility and excretion can be influenced by urine pH. By increasing the pH of the urine through alkalinization, salicylate becomes more ionized. Ionized drugs are less likely to be reabsorbed in the renal tubules and more easily eliminated from the body through urine. This mechanism helps to enhance the clearance of toxic levels of salicylates, effectively reducing their concentration in the bloodstream and alleviating toxicity.

The other options do not directly relate to the mechanism by which urinary alkalinization reduces salicylate toxicity, nor do they address the primary goal of treating overdoses of these medications.