What laboratory value indicates salicylate toxicity in this patient?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

A salicylate level of 50 mg/dL indicates salicylate toxicity in a patient. Salicylates, such as aspirin, are commonly associated with toxicity when blood concentrations exceed therapeutic levels. Typically, therapeutic levels of salicylates are considered to be below 30 mg/dL; levels above this threshold, especially approaching 50 mg/dL and higher, can lead to serious toxicity, manifested by symptoms such as tinnitus, dizziness, and metabolic acidosis.

The values of phenytoin, blood glucose, and electrolyte imbalance do not specifically indicate salicylate toxicity. Phenytoin levels are related to the monitoring of patients on antiepileptic therapy, blood glucose levels indicate carbohydrate metabolism rather than salicylate presence, and electrolyte imbalances are common in various conditions but are not specific markers for salicylate toxicity. Therefore, when evaluating the potential for salicylate toxicity, the salicylate level is critical, making a level of 50 mg/dL indicative of a toxic state.

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