What physiological change is expected when the sympathetic system is inhibited using a pharmacological agent?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

When the sympathetic nervous system is inhibited by a pharmacological agent, one of the primary physiological responses observed is a reduction in heart rate. The sympathetic nervous system is responsible for the "fight or flight" response, which includes increasing heart rate to supply more blood to the muscles and vital organs in times of stress or danger. When this system is inhibited, the opposing effects of the parasympathetic nervous system become more dominant. The parasympathetic system promotes a "rest and digest" state, leading to a decrease in heart rate as it works to conserve energy and facilitate bodily functions such as digestion.

The other physiological changes that could be expected, such as increases in blood pressure, decreases in fluid secretions, and constriction of blood vessels, typically result from sympathetic activation. Inhibition of the sympathetic system would generally lead to the opposite effects: lower blood pressure and increased vascular dilation, alongside increased secretions as the body enters a more relaxed state. Thus, the reduction in heart rate aligns perfectly with the effects of sympathetic inhibition.

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