Which agent is the most appropriate choice for emergency contraception after unprotected intercourse?

Levonorgestrel is recognized as the most appropriate choice for emergency contraception following unprotected intercourse. This progestin works primarily by inhibiting or delaying ovulation, thereby preventing fertilization. For optimal efficacy, it should be taken as soon as possible after the unprotected sexual encounter, ideally within 72 hours, but it can be effective up to 5 days later.

Levonorgestrel has been extensively studied and is accessible over-the-counter in many locations, making it a convenient option for individuals seeking emergency contraception. Its mechanism of action is specifically tailored to address the need for timely intervention to reduce the risk of pregnancy after unprotected intercourse.

Other agents, while they may have certain roles in reproductive health or abortion provision, do not serve as frontline options for emergency contraception in the same manner as levonorgestrel. Ethinyl estradiol combined with a progestin such as norgestimate is typically used in regular contraceptive formulations and not for emergency situations; it also carries a higher risk of side effects if used for this purpose. Etonogestrel is generally available as a contraceptive implant and is not indicated for emergency use. Mifepristone is effective for medical abortion rather than preventing pregnancy after un