Which drug is correctly matched with its associated adverse effect?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

Nitrofurantoin is indeed correctly matched with pulmonary fibrosis. This adverse effect is particularly associated with long-term use or in patients with pre-existing lung conditions. Nitrofurantoin is an antibiotic commonly used to treat urinary tract infections, and while it is generally well-tolerated, chronic exposure can lead to lung toxicity, which is characterized by pulmonary fibrosis.

This condition occurs as a result of reactive metabolite formation and the subsequent inflammatory response in the lung tissue, potentially leading to symptoms such as dyspnea, cough, and decreased lung function over time. It's important for healthcare providers to monitor patients, especially those who are on Nitrofurantoin for extended periods, for signs of respiratory complications.

In contrast, the other drugs listed have different adverse effect profiles that do not match correctly with their respective medications, highlighting the importance of understanding the safety and side effect spectra of various pharmacological agents.

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