Which medication is an SNRI that can be used for depression accompanied by pain symptoms?

Duloxetine is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI), and it is particularly notable for its efficacy in treating both depression and pain symptoms, such as those associated with fibromyalgia or diabetic neuropathy. The dual action of duloxetine on both serotonin and norepinephrine neurotransmitters makes it effective for individuals who experience mood disorders alongside chronic pain. This combination addresses both components of their condition, potentially leading to improved overall outcomes.

In contrast, fluoxetine and sertraline are selective serotonin reuptake inhibitors (SSRIs), primarily targeting serotonin levels, which may not provide the same effectiveness for pain management as duloxetine does. Phenelzine, an MAOI, is typically used in specific cases of depression but does not have the dual action on pain that duloxetine offers. Thus, duloxetine stands out as the appropriate choice for this scenario.