Which of the following agents is a dopamine receptor agonist?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

Bromocriptine is classified as a dopamine receptor agonist, specifically targeting postsynaptic dopamine D2 receptors. It is commonly used in the treatment of conditions such as Parkinson's disease and hyperprolactinemia. By mimicking the action of dopamine in the brain, bromocriptine can help alleviate some of the symptoms associated with low dopamine levels, such as rigidity and bradykinesia in Parkinson's patients. Dopamine receptor agonists are crucial in managing these disorders, as they can enhance dopaminergic signaling in the absence of sufficient endogenous dopamine.

Other agents mentioned, such as carbidopa, are not dopamine agonists; instead, carbidopa is used primarily as a peripheral decarboxylase inhibitor that prevents the conversion of levodopa to dopamine outside of the central nervous system. Rivastigmine is an acetylcholinesterase inhibitor used in the treatment of Alzheimer's disease and does not interact with dopamine receptors. Memantine is an NMDA receptor antagonist, also utilized for Alzheimer's disease but operates through a different mechanism than dopamine agonism. The properties and functions of each of these drugs highlight why bromocriptine stands out as the dopamine receptor agonist in this group.

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