Which statement is correct regarding trichogenic agents?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

The statement about finasteride inhibiting the 5-α reductase enzyme that controls DHT production is correct because it accurately describes the mechanism by which finasteride acts. Dihydrotestosterone (DHT) is an androgen hormone that contributes to hair loss in conditions such as androgenetic alopecia. Finasteride specifically inhibits the Type II 5-α reductase enzyme, leading to a decrease in DHT levels. By reducing DHT production, finasteride helps slow hair loss and can promote regrowth in some men experiencing pattern baldness.

The other statements do not accurately convey the effects or mechanisms of the agents discussed. Minoxidil, while it does promote hair growth and has some systemic effects, is primarily recognized for its vasodilatory properties rather than hypotensive effects when used topically. Additionally, minoxidil does not maintain hair growth after discontinuation; instead, any new hair growth typically reverts to the baseline if the treatment is stopped. Lastly, while minoxidil is indeed available in topical formulations for alopecia, its oral form is not commonly prescribed for this purpose due to potential systemic side effects.

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