Which topical treatment is commonly used for acne due to its keratolytic properties?

Prepare for the Lippincott Pharmacology Exam with interactive flashcards and multiple-choice questions, each accompanied by detailed hints and explanations. Master your exam with ease!

Salicylic acid is widely used as a topical treatment for acne primarily because of its keratolytic properties. This means that it helps to loosen and remove dead skin cells from the surface of the skin as well as from within the pores, preventing the clogging that can lead to acne formation. By enhancing the shedding of the outermost layer of skin, salicylic acid can reduce the formation of comedones (blackheads and whiteheads) and improve overall skin texture.

Additionally, salicylic acid has anti-inflammatory properties, which can help reduce the redness and swelling associated with acne lesions. Its ability to penetrate pores and dissolve excess sebum makes it particularly effective for acne treatment, making it a go-to option for many dermatologists and skin care experts.

In contrast, while clindamycin is an antibiotic that helps reduce the population of acne-causing bacteria, it does not have keratolytic effects. Metronidazole is primarily effective against certain bacterial and protozoal infections and is used for rosacea rather than typical acne. Azelaic acid also has some keratolytic properties, along with anti-inflammatory and antibacterial effects, but salicylic acid is typically more recognized for its direct coagulation of keratin

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